Dr Paul Brennan

Dr Paul Brennan

BMedSci(Hons), MBBS, FRCP

Clinical Genetics

27 years of experience
18 years as a specialist

Overall Rating

Overall
5
Bedside Manner
5
Explanation
5

Top feedback

“Dr Brennan had bad news for us but he delivered it with great respect and knowledge. He is the nicest doctor I’ve ever had the pleasure of meeting ( and I’m a nurse! ) “
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Languages spoken

  • English
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Registered with

  • General Medical Council: 3677959
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    Consultation fees

    New appointment: £350

    Follow-up appointment: £250

    Practices worked at

    The Harley Street Clinic

    35 Weymouth Street, london, United Kingdom, W1G
    159 reviews

    About

    Dr Brennan's main areas of expertise are cancer, cardiac and endocrine genetics.

    His interest in genetics started as a medical student in the 1980s when the medical speciality of clinical genetics was in its infancy. After a research degree studying genes in the developing heart, he completed his medical training and undertook postgraduate training in adult medicine and paediatrics before specialist training in Clinical Genetics.

    Dr Brennan was appointed as an NHS Consultant in Clinical Genetics in 2002 with the Northern Genetics Service based in Newcastle upon Tyne. After opening a new satellite clinical genetics department in Middlesbrough, he was appointed to the role of Clinical Director of the Northern Genetics Service in 2008, managing a clinical and laboratory team providing genetics diagnostics for the population of North East England and North Cumbria.

    Dr Brennan has been Clinical Lead for Cardiac and Endocrine Genetics for the Northern Genetics Service since 2003; he was Clinical Lead for Cancer Genetics 2002 to 2020. 

    A particular interest is the use of new technology and novel clinical pathways to improve diagnosis and management for people living with rare inherited disease. Between 2014 and 2018 he was Clinical Programme Director for the North East & North Cumbria NHS Genomic Medicine Centre, overseeing the introduction of whole genome sequencing into routine care as part of the 100,000 Genomes Project. He is engaged in a number of collaborative research projects, all of which are focused on improving diagnosis and treatment.

    Dr Brennan is a keen and popular teacher and lectures to a wide range of undergraduate and postgraduate audiences in the UK and overseas. He teaches genetics for a week each year at Newcastle University's Medical School in Malaysia.

    www.genomics.expert

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    Special interests

    Dr Brennan has a long experience of diagnosing and managing hereditary diseases in adults and young people. In addition to general genetic problems such as chromosome abnormalities and infertility, his specialist areas are:

    A. Inherited cardiovascular disorders, for example:

    • Brugada syndrome
    • Long QT syndrome
    • Familial hypertrophic and dilated cardiomyopathy
    • Arrhythmogenic right ventricular cardiomyopathy
    • Sudden unexplained death
    • Familial thoracic aortic aneurysm
    • Marfan syndrome, Loeys Dietz syndrome and Meester-Loeys syndrome
    • Vascular Ehlers Danlos syndrome

    B. Inherited connective tissue disorders, including

    • classical Ehlers Danlos syndrome
    • hypermobile Ehlers Danlos syndrome

    C. Inherited cancer syndromes, for example:

    • Hereditary breast/ovarian cancer
    • Cowden's disease
    • Lynch syndrome
    • Familial Adenomatous Polyposis
    • Hereditary leiomyomatosis / renal cell carcinoma syndrome
    • Birt Hogg Dube syndrome
    • Li Fraumeni syndrome

    C. Inherited endocrine syndromes, for example:

    • Familial paragangliomatosis
    • Von Hippel Lindau disease
    • Multiple endocrine neoplasis types 1 & 2 and familial medullary thyroid cancer)

    D. Inherited skin disorder, for example:

    • Hereditary skins cancers
    • Neurofibromatosis
    • Birt Higg Dube syndrome

     

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    Education

    • Bachelor of Medical Science (Human Genetics) Newcastle University
    • Bachelor of Medicine and Bachelor of Surgery, Newcastle University

    Professional Qualifications:

    • MRCP (Edinburgh)
    • FRCP (London)
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    Reviews

    5 Overall Patient Trust rating
    Overall Experience
    Explanation
    Bedside Manner
    Clinical Genetics
    8/53
    Genetic Consultation
    8/53
    Hypermobility Syndrome
    6/53
    ehlers-danlos syndrome (EDS)
    5/53
    Ehlers-Danlos Syndrome (EDS)
    4/53
    Dhlers-Danlos Syndrome (EDS)
    3/53
    Genetic Procedures
    2/53
    Hypermobile Ehlers-Danlos Syndrome
    2/53
    Marfan Syndrome
    2/53
    hEDS
    2/53
    Breast Cancer
    1/53
    Cancer Genetics
    1/53
    Ehlers Danlos Syndrome
    1/53
    Ehlers-Danlos syndrome
    1/53
    Ehlers-Danloss Test
    1/53
    Genetic Testing
    1/53
    Genetic Testing - Epilepsy
    1/53
    Heds
    1/53
    Hyypermobile Ehler's Danlos
    1/53
    Male Infertility
    1/53
    SCA-6
    1/53
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    Sort by:
    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Hypermobility Syndrome
    Dr Brennan had bad news for us but he delivered it with great respect and knowledge. He is the nicest doctor I’ve ever had the pleasure of meeting ( and I’m a nurse! )
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Genetic Testing - Epilepsy
    Dr Brennan was incredibly personable, explaining genetic testing in way that helped me to understand. Dr Brennan couldn’t have been more helpful and I appreciate his input with my daughter. Thank you.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Genetic Consultation
    Dr Brennan was very knowledgeable and explained things in an accessible way. He put both my husband and myself at ease and was a pleasure to deal with.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Genetic Testing
    Dr Brennan was incredibly professional, personable, empathic and helpful. He presented very complex information in an accessible way. I am very grateful for his consultation. Thank you
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Clinical Genetics
    My experience with Dr Brennan was that he gave me as much time as I needed to explain my concerns. He was considered and thorough with his explanations. I took great comfort in his expertise. I found him to be an empathetic and caring doctor.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Clinical Genetics
    Paul Brennan is a quiet and gentle person who exudes patience and offers time and something we are definitely not used to: a listening ear. He asks a question and waits to hear the reply! My daughter and I felt heard, respected and Midge's experiences were validated. The clinic letter was sent in a timely fashion. Paul's receptionist is absolutely lovely too. Paul has even been in touch since our original appointment when we had issues with our paediatrician. I honestly can't recommend him highly enough. I regularly recommend Paul to other people struggling to get a diagnosis through the NHS. Thanks Paul
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Cancer Genetics
    Dr Brennan was wonderful - he fully explained the process of genetic testing and the implications of the results for myself and our family in a way that enables us to make an informed decision about proceeding with the test.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Ehlers-Danlos Syndrome (EDS)
    Very polite, clearly knows what he is talking about! Explained in detail to me and was not rushed. I was presented with options and an honest opinion. This allowed an informed decision on next steps. Reassuring Dr knew some of my other consultants. Dr could have taken advantage to get more sessions but the honest and explained reasoning basically informed me that the value to me of having further tests was low. I really recommend Dr Brennan. Perhaps a bit strange to say, but I really enjoyed my visit and left with options and hope.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    SCA-6
    I saw Dr Brennan for some genetic testing for a rare condition that I recently discovered I may have inherited. I cannot speak highly enough of him for the manner in which he handled a very difficult situation. He was incredibly knowledgeable but arguably more importantly, struck the perfect balance of reassurance and realism.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Ehlers-Danlos Syndrome (EDS)
    Dr. Brennan was the first positive experience of a medical professional that I've had in over 12 years. He listened to my concerns, validated them and took me seriously. He provided clear explanations for my chronic symptoms, and advised on the necessary investigations to confirm a diagnosis and manage potential risk. I finally have the correct explanation for my difficulties (though more research Is needed!) and a treatment plan to ensure that I get the right care to manage my conditions moving forwards. I can't thank you enough, and I'm sure I will be in contact again for more advice in the future.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    My two children and I saw Dr Brennan for assessment of hEDS. I found Dr Brennan extremely thorough and knowledgeable- and he was able to also engage our autistic son well. Dr Brennan had a good understanding of the difficulties we faced as a family unit and provided reassurance and validation. A very nice doctor to see - we would highly recommend.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Ehlers-Danlos Syndrome (EDS)
    Highly recommended- We travelled as a family from Northern Ireland to Dr Brennan’s London clinic, in regard to our 17 year old son. Dr Brennan immediately put us at ease and was extremely patient as he listened to an extensive medical history and summary of our journeys towards diagnoses, including my own diagnosis of Ehlers-Danlos Syndrome (EDS). Dr Brennan examined our son and made a clinical diagnosis of hEDS. We arranged a further appointment for our 14 year old daughter and we experienced the same level of professionalism. Once again there was a diagnosis of hEDS; followed by a comprehensive report for us to share with our health professionals. We really appreciated his kind and caring approach and would highly recommend Dr Brennan to anyone concerned that they may have EDS.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Genetic Consultation
    Dr Brennan is a very professional and kind person. Highly recommended
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Ehlers-Danlos Syndrome (EDS)
    I saw Dr Brennan to get his expert opinion on what I thought was probably hypermobile Ehlers-Danlos Syndrome but had been severely invalidated by numerous NHS specialist teams I've seen. I'm very complex (or a few others might say "complicated") and have signifiant history of mental health issues. I am aware EDS is notoriously hard to get validated as a diagnosis, but because of my MH issues, specialists were even more keen to conclude "its in your head because of you past traumas". I am still on a diagnostic journey with my different specialists trying to get them on board with my physical problems being linked to EDS, its only the mere start but thanks to Dr Brennan's specialist knowledge and excellent clinic letter this is really going to help on this complicated journey! Dr Brennan is very caring, validating and very knowledgeable. His clinic letter was so refreshing that unlike all other clinic letters didn't start off going off on one about my "significant mental health issues".... Thank you for the validation I so desperately needed! Life changing. Literally!
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Genetic Consultation
    Great consultation over the phone, Dr. Brennan was very detailed and allowed time for questions. I also got a digital consultation report within the day for my records.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Genetic Consultation Male Infertility
    Couldn’t recommend highly enough. We had an extremely complex issue which Dr. Brennan explained throughly to use, and was followed up with a comprehensive report. We didn’t feel rushed, and had enough time to ask many, many, questions.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Clinical Genetics
    Great and informative appointment. Dr Brennan was extremely helpful, answered all my questions and provided great assurance throughout the appointment and testing process.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Clinical Genetics
    My wife and I booked an appointment with Dr Brennan who made himself available at a convenient time for us. He was very clear in his explanation of our particular issue and has been very helpful in his follow up with the next steps. I would certainly recommend Dr Brennan
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Clinical Genetics
    Although I had a short interaction with Dr. Brennan I found his explanation very clear. He was very interested in my family history and my concern relating to breast cancer risk. He presented to me with a graphical support the various genes which may impact the development of risk cancer and recommended, based on his experience, the best test that I should take. I felt very comfortable in his presence and trust his experience and knowledge in the matter.
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    Overall
    (5/5)
    Explanation
    (5/5)
    Bedside Manner
    (5/5)
    Patient seen for:
    Clinical Genetics
    Extremely professional and ensured the patient was at ease through out the consultation. Prompt with intimating results, and very comprehensive in his consultation. I would strongly recommend Dr Brennan.
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